HomeComputerHow to Disable Startup Programs in Windows. How to Disable Startup Programs in Windows. 0 NASAAR MUNZIR AHAMED 7:45 PM 1.Open Run Window Type Msconfig Click Enter. 2. You Get a New Window. 3. Select the Startup Option. 4. Change Enabled to Disable Option Don't Change Windows Defender to Disable. Tags Computer Newer Older